Profiling systemic physiology through blood‐based multidimensional RNAseq
نویسندگان
چکیده
منابع مشابه
RNAseq Transcriptional Profiling following Whip Development in Sugarcane Smut Disease
Sugarcane smut disease is caused by the biotrophic fungus Sporisorium scitamineum. The disease is characterized by the development of a whip-like structure from the primary meristems, where billions of teliospores are produced. Sugarcane smut also causes tillering and low sucrose and high fiber contents, reducing cane productivity. We investigated the biological events contributing to disease s...
متن کاملRNASeq Analysis
3 Statistical issues 3 3.1 Experimental design . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 3.2 Batch effects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 3.3 Summarizing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 3.4 Normalization . . . ...
متن کاملProfiling the macrofilaricidal effects of flubendazole on adult female Brugia malayi using RNAseq
The use of microfilaricidal drugs for the control of onchocerciasis and lymphatic filariasis (LF) necessitates prolonged yearly dosing. Prospects for elimination or eradication of these diseases would be enhanced by the availability of a macrofilaricidal drug. Flubendazole (FLBZ), a benzimidazole anthelmintic, is an appealing candidate. FLBZ has demonstrated potent macrofilaricidal effects in a...
متن کاملTransforming Medicine Through Physiology
Claude Bernard is considered by many to be the father of modern physiology and medicine. In his 1865 book, An Introduction to the Study of Experimental Medicine, Bernard introduced the scientific method to the field of medicine and thereby initiated the concept of evidenced-based medicine. In this approach, physiological research focuses on finding solutions for clinical problems through hypoth...
متن کاملRNAseq Differential Expression Analysis
Dataset taken from Somel et al. 2012: (check publication for details) • 3 human + 3 chimp brain transcriptome data • Illumina RNA-Seq, paired-end 76bp • Reads mapped to human and chimp genome and reads counted for each transcript Download the following data files into a directory of your choice (e.g. data): • Human: http://www.nowick-lab.info/wp-content/uploads/2013/12/segemehl.hg19.readCount.t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2021
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.2021.35.s1.03868